Chronic viral hepatitis is caused mainly by chronic infection with hep
atitis viruses B (HBV), C (HCV), or delta (HDV). Persons chronically i
nfected with one or more of these viruses may develop chronic progress
ive hepatitis, cirrhosis, and liver failure. In addition, chronic HBV
and HCV infections are major causal risk factors for hepatocellular ca
rcinoma. Alcohol consumption accelerates the development of chronic li
ver disease among HCV-infected individuals and may have similar effect
s on persons chronically infected with HBV alone or HBV and HDV, but t
he reported studies are inconsistent.