Retention of a single salt solution was investigated versus the applie
d pressure, ion valencies and feed concentration using positively-char
ged membranes, obtained by chemical modification of ZrO2 layer of UF m
embranes with a cross-linked polymer. Retention of colon was in agreem
ent with the Donnan effect but coupling with either divalent counterio
n or the smallest colon (proton) was not accounted for. Mixtures of bi
g positive organic solutes (antibiotics) and small cations were studie
d at increasing ionic strength (I). Retentions of membrane colons were
plotted versus I--0.5 according to the semi-empirical model of ionic
strength controlled retention the applicability of which was discussed
and compared to the Donnan effect.