CHIRAL RESOLUTION OF THE DANSYL DERIVATIVE OF 2-METHYLTAURINE BY CAPILLARY ELECTROPHORESIS

Authors
ANSELMI S BRAGHIROLI D DIBELLA M SCHMID MG WINTERSTEIGER R GUBITZ G
Citation
S. Anselmi et al., CHIRAL RESOLUTION OF THE DANSYL DERIVATIVE OF 2-METHYLTAURINE BY CAPILLARY ELECTROPHORESIS, Journal of chromatography B. Biomedical applications, 681(1), 1996, pp. 83-86
Citations number
9
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Journal of chromatography B. Biomedical applications
ISSN journal
15726495 → ACNP
Volume
681
Issue
1
Year of publication
1996
Pages
83 - 86
Database
ISI
SICI code
Abstract
A cyclodextrin-modified micellar capillary electrophoretic method was developed for the chiral separation of 2-methyltaurine. The racemic mi xture was separated after derivatization with dansyl chloride. The ena ntiomeric separation of the dansyl derivative was done using electroly te solutions containing beta-cyclodextrin (beta-CD) or different ratio s of beta- and gamma-CD. The mixture of beta- and gamma-CD optimally r esolved the compound studied.