FOLLOW-UP OF BONE-LESIONS IN AN EXPERIMENTAL MULTIPLE-MYELOMA MOUSE MODEL - DESCRIPTION OF AN IN-VIVO TECHNIQUE USING RADIOGRAPHY DEDICATEDFOR MAMMOGRAPHY

The evolution of bone lesions in transplantable C57BL/KaLwRij 5T mouse myeloma (MM) has been followed in vivo. Mice were anaesthetised and a radiograph of the pelvis and hind legs was performed by a radiograph dedicated for mammography. This is the first description of an in vivo technique under experimental conditions whereby the development of bo ne lesions owing to the MM growth was demonstrated.