Objectives: To determine more closely the relationship between vasomot
or symptoms, well-being and climacteric status according to the last m
enstrual bleeding and according to the women themselves. Methods: A po
pulation-based cross-sectional study was executed using a postal quest
ionnaire. Well-being of women with and without vasomotor symptoms was
compared, for the different menopausal statuses. All 2729 women living
in a commuter suburb of Rotterdam aged 45-60 years were approached of
whom 1947 (71.3%) responded. Well-being was measured by the Inventory
of Subjective Health (ISH) and three subscales of the Sickness Impact
Profile (SIP). Results: The results showed that the relationship betw
een vasomotor symptoms and well-being was dependent on climacteric sta
tus. Pre- and (middle and late) postmenopausal women with vasomotor sy
mptoms more often experienced a relatively lower level of well-being c
ompared to women without these symptoms. However, when the prevalence
of vasomotor symptoms is as its peak, i.e. in late perimenopause, a di
fference in the level of well-being between women with and without vas
omotor symptoms was absent. Conclusions: It is concluded that well-bei
ng and vasomotor symptoms were inversely related in all menopausal sta
tuses except for the (late) perimenopausal phase. For this no somatic
explanation seems plausible. A more social scientific explanation is s
uggested.