Organ transplantation and the use of immunosuppressive therapy has bee
n associated with an increased incidence of malignancy. We report the
case of a long-term renal transplant recipient who developed concomita
nt skin cancers, non-Hodgkin's lymphoma, and malignant fibrous histioc
ytoma. The development of three seemingly unrelated cancers in the sam
e patient illustrates the favorable host environment in transplant pat
ients for the development of malignancies.