CLINICAL AND PATHOLOGICAL FEATURES OF PROTEIN-LOSING GLOMERULAR-DISEASE IN THE DOG - A REVIEW OF 137 CASES (1985-1992)

Medical records of 137 dogs with protein-losing glomerular disease (PL GD) were evaluated. Cases with amyloidosis (23%) were more likely to b e azotemic at presentation, with significantly greater proteinuria and hypoalbuminemia than those cases with glomerulonephritis (GN; 77%). T he prognosis for all cases was poor, with a median survival time of ju st 28 days. The most common causes of death in cases with idiopathic d isease were chronic renal failure (69.5%) or thromboembolic complicati ons (22.2%). Progression of glomerular disease was unpredictable, with no apparent correlation between survival time and biochemical paramet ers at presentation.