ORGANOPHOSPHORLE COMPOUNDS HAVING BETA-CY ANOETHYL-TYPE STRUCTURAL ELEMENTS .2. YL-N,N-BIS(BETA-CYANOETHYL)AMINO-ALKANEPHOSPHONATE SYNTHESIS

The paper describes a method for the O,O-dimethyl-N,N-bis (beta-cyanoe thyl) amino-methanophosphonate preparation, following the Kabachnik-Fi elds type reaction between: dimethylphosphite, formaldehyde and N,N-bi s (beta-cyanoethyl) amine. In the optimum management of a synthesis pr ocess it is essential to inhibit the secondary, dimethylphosphite hydr olysis reaction, by avoiding the water presence in the reacting system during the dialkyphosphite addition. Thus we proceeded to the methano l esterification of the methylhydroxylamine resulting from the N,N-bis (beta-cyanoethyl) amine and formaldehyde reaction.