POSTOPERATIVE NAUSEA AND VOMITING - PROPOFOL OR THIOPENTONE - DOES CHOICE OF INDUCTION AGENT AFFECT OUTCOME

Authors
MYLES PS HENDRATA M BENNETT AM LANGLEY M BUCKLAND MR
Citation
Ps. Myles et al., POSTOPERATIVE NAUSEA AND VOMITING - PROPOFOL OR THIOPENTONE - DOES CHOICE OF INDUCTION AGENT AFFECT OUTCOME, Anaesthesia and intensive care, 24(3), 1996, pp. 355-359
Citations number
18
Categorie Soggetti
Anesthesiology,"Emergency Medicine & Critical Care
Journal title
Anaesthesia and intensive care → ACNP
ISSN journal
0310057X
Volume
24
Issue
3
Year of publication
1996
Pages
355 - 359
Database
ISI
SICI code
0310-057X(1996)24:3<355:PNAV-P>2.0.ZU;2-4
Abstract
Postoperative nausea and vomiting (PONV) has many causes, including an aesthetic drugs. Choice of induction agent may affect the incidence of PONV, though the evidence is conflicting. We have analysed our databa se of outcome after surgery. Data on 4173 patients were analysed using multivariate logistic regression, with an overall incidence of PONV 2 1.3%. Propofol, when compared to thiopentone for induction of anaesthe sia, resulted in an 18% reduction in PONV (OR=0.82, P=0.03), The likel y postoperative benefits of propofol may outweigh concerns about its a dditional cost.