Non-insulin-dependent diabetes mellitus (NIDDM) is one of the most com
mon metabolic and endocrine disorders in developed countries. NIDDM is
a multifactorial disorder in which genetic factors play a complex rol
e in its development, Until recently, little has been known of the gen
etic determinants of NIDDM, Advances in molecular biological and molec
ular genetic approaches have now made it possible to begin to identify
the diabetes susceptibility genes in NIDDM. This review describes the
progress of recent research in the molecular genetic aspects of NIDDM
.