MARKED ARTERIOSCLEROSIS OF THE DESCENDING AORTA IN A TEENAGER WITH INTERRUPTION OF THE AORTA

Marked arteriosclerosis localized to the descending thoracic and abdom inal aorta was observed in a 19-year-old girl with interruption of the aorta (type A) and a ventricular septal defect, She died from rupture of saccular aneurysm of the pulmonary trunk, The descending thoracic and abdominal aorta showed marked thrombogenic, lamellar thickening of the intima, In contrast, no significant arteriosclerosis was detected in the ascending aorta, Several factors including diffuse sludging of blood, mural thrombosis and hemodynamic changes, in close association with poly-cythemia, are hypothesized to be causative factors in the d evelopment of this lesion.