Juxtaposed between the posterior nasal cavity and skull base, the dise
ased sphenoid sinus presents unique challenges when surgical drainage
is required, Endoscopic techniques have gained widespread popularity f
or the treatment of sphenoid sinusitis, yet the efficacy of such treat
ment remains largely unknown, Thirty-four patients who underwent endos
copic sphenoidotomy were monitored over a period of 6 months to 5 year
s. Surgery was performed with the superior turbinate used as the key l
andmark for identification and enlargement of the natural sphenoid ost
ium, Surgical access was through either a transnasal or transethmoid a
pproach, depending on whether disease was limited to the sphenoid sinu
s, Prospective analysis of 26 patients with established outcome measur
es demonstrated a significant reduction in facial pain, nasal drainage
, and congestion 6 months after surgery (p < 0.0001). Medication use w
as also reduced but to a lesser extent (p < 0.05), Endoscopic sphenoid
otomy appears to be a safe technique that effectively reduces patient
morbidity associated with sphenoid sinusitis.