SYNTHESIS OF ENANTIOMERICALLY PURE HYDROXYETHYLPORPHYRINS AND THEIR TRANSFORMATION INTO OPTICALLY-ACTIVE CHLORIN DERIVATIVES .4.

Authors
KUSCH D MONTFORTS FP
Citation
D. Kusch et Fp. Montforts, SYNTHESIS OF ENANTIOMERICALLY PURE HYDROXYETHYLPORPHYRINS AND THEIR TRANSFORMATION INTO OPTICALLY-ACTIVE CHLORIN DERIVATIVES .4., Liebigs Annalen, (1), 1996, pp. 83-86
Citations number
29
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen → ACNP
ISSN journal
09473440
Issue
1
Year of publication
1996
Pages
83 - 86
Database
ISI
SICI code
0947-3440(1996):1<83:SOEPHA>2.0.ZU;2-1
Abstract
The oxazaborolidine (9)-catalyzed reduction of acetylporphyrins (4) le d to enantiomerically pure hydroxyethylporphyrins (5), which were tran sformed into optically active chlorin derivatives (7 and 8) upon react ion by N,N-dimethylacetamide dimethyl acetal followed by hydrogenation . The absolute configuration of the synthesized chlorins was elucidate d by means of their CD spectra.