STEREOSELECTIVE DIOXYGENASE-CATALYZED BENZYLIC HYDROXYLATION AT PROCHIRAL METHYLENE GROUPS IN THE CHEMOENZYMATIC SYNTHESIS OF ENANTIOPURE VICINAL AMINOINDANOLS

Authors
BOYD DR SHARMA ND BOWERS NI GOODRICH PA GROOCOCK MR BLACKER AJ CLARKE DA HOWARD T DALTON H
Citation
Dr. Boyd et al., STEREOSELECTIVE DIOXYGENASE-CATALYZED BENZYLIC HYDROXYLATION AT PROCHIRAL METHYLENE GROUPS IN THE CHEMOENZYMATIC SYNTHESIS OF ENANTIOPURE VICINAL AMINOINDANOLS, Tetrahedron : asymmetry, 7(6), 1996, pp. 1559-1562
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
6
Year of publication
1996
Pages
1559 - 1562
Database
ISI
SICI code
0957-4166(1996)7:6<1559:SDBHAP>2.0.ZU;2-1
Abstract
Enantiopure benzylic alcohols containing two stereogenic centres in a cis-relationship result from stereoselective monohydroxylation of achi ral 2-substituted indans in cultures of Pseudomonas putida UV4 and are used in the chemoenzymatic synthesis of both cis- and trans-aminoinda nol enantiomers. (C) 1996 Elsevier Science Ltd