STEREOSELECTIVE SYNTHESIS OF (S)-(-ALPHA-M4CPG, A SELECTIVE ANTAGONIST OF METABOTROPIC GLUTAMATE RECEPTORS())

Authors
MA DW TIAN HQ
Citation
Dw. Ma et Hq. Tian, STEREOSELECTIVE SYNTHESIS OF (S)-(-ALPHA-M4CPG, A SELECTIVE ANTAGONIST OF METABOTROPIC GLUTAMATE RECEPTORS()), Tetrahedron : asymmetry, 7(6), 1996, pp. 1567-1570
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
6
Year of publication
1996
Pages
1567 - 1570
Database
ISI
SICI code
0957-4166(1996)7:6<1567:SSO(AS>2.0.ZU;2-O
Abstract
The synthesis, from (R)-4-hydroxyphenylglycine, of(+)-alpha-methyl-4-c arboxy-phenylglycine ((+)-alpha M4CPG), a new and selective antagonist of metabotropic glutamate receptor, and assignment of its absolute co nfiguration, are described. (C) 1996 Elsevier Science Ltd