ASYMMETRIC REDUCTION OF 2-OXO-4-PHENYLBUTANOIC ACID ETHYL-ESTER BY DAUCUS-CAROTA CELL-CULTURES

Authors
CHADHA A MANOHAR M SOUNDARARAJAN T LOKESWARI TS
Citation
A. Chadha et al., ASYMMETRIC REDUCTION OF 2-OXO-4-PHENYLBUTANOIC ACID ETHYL-ESTER BY DAUCUS-CAROTA CELL-CULTURES, Tetrahedron : asymmetry, 7(6), 1996, pp. 1571-1572
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
6
Year of publication
1996
Pages
1571 - 1572
Database
ISI
SICI code
0957-4166(1996)7:6<1571:ARO2AE>2.0.ZU;2-7
Abstract
A novel method to produce (R)-(-)-2-hydroxy-4-phenylbutanoic acid ethy l ester 1b has been developed. 2-Oxo-4-phenylbutanoic acid ethyl ester 1a is reduced to 1b by the cell cultures of Daucus carota in high ena ntiomeric excess and yield. (C) 1996 Elsevier Science Ltd