RESOLUTION OF RACEMIC 1,3-DISUBSTITUTED PROPANOLS BY (R,R)-DI-(4-TOLUOYL)-TARTARIC ACID - SIMILAR CONDITIONS FOR SIMILAR STRUCTURES

Authors
GIZUR T PETERI I HARSANYI K FOGASSY E
Citation
T. Gizur et al., RESOLUTION OF RACEMIC 1,3-DISUBSTITUTED PROPANOLS BY (R,R)-DI-(4-TOLUOYL)-TARTARIC ACID - SIMILAR CONDITIONS FOR SIMILAR STRUCTURES, Tetrahedron : asymmetry, 7(6), 1996, pp. 1589-1590
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
6
Year of publication
1996
Pages
1589 - 1590
Database
ISI
SICI code
0957-4166(1996)7:6<1589:ROR1PB>2.0.ZU;2-J
Abstract
The resolution of structurally similar (+/-)-1-[4-(4- yl)-phenyl]-3-(4 -phenyl-1,2,3,6-tetrahydropyridin- 1-yl)-1-propanol and 1'-biphenyl-4- yl)-3-[4-(4-fluorophenyl)-piperazin- 1-yl]-1-propanol was accomplished by (R,R)-di-(4-toluoyl)-tartaric acid in methanol. The experiments il lustrate the possibilities for selecting the resolving agent for a rac emate which is available in insufficient quantity by making the trial experiments on a structurally similar racemates. (C) 1996 Elsevier Sci ence Ltd