STUDIES ON QUINAZOLINES .6. ASYMMETRIC-SYNTHESIS OF 5-METHYLTHIO-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES AND ETHYLTHIO-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES())
A. Gutcait et al., STUDIES ON QUINAZOLINES .6. ASYMMETRIC-SYNTHESIS OF 5-METHYLTHIO-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES AND ETHYLTHIO-2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES()), Tetrahedron : asymmetry, 7(6), 1996, pp. 1641-1648
The titled compounds have been synthesized in five steps from commerci
ally available (R)-(+) and (S)-(-)-glycidol. The overall yield was abo
ut 29% with ee>98.5 %. Copyright (C) 1996 Elsevier Science Ltd