A methodology for the modelling of wastewater treatment plants by acti
vated sludge is proposed. It takes into account the strong coupling be
tween hydrodynamics and biological reactions. Hydrodynamical modelling
makes use of residence time distributions obtained by tracing the dif
ferent units (primary settler, aeration tank and secondary clarifier)
with lithium chloride. The biological model is based on IAWPRC Task Gr
oup Model 1. Simulated time and space profiles are in good agreement w
ith experimental data, taken on an existing full-scale plant.