PURIFICATION AND PARTIAL CHARACTERIZATION OF PROTEINS PRESENT IN A PERCHLORIC-ACID EXTRACT OF GOAT LIVER (UK101)

Authors
BARTORELLI A BIANCARDI C CAVALCA V FERRARA R BOTTA M ARZANI C COLOMBO I BERRA B CECILIANI F RONCHI S BAILO M
Citation
A. Bartorelli et al., PURIFICATION AND PARTIAL CHARACTERIZATION OF PROTEINS PRESENT IN A PERCHLORIC-ACID EXTRACT OF GOAT LIVER (UK101), Journal of tumor marker oncology, 11(1), 1996, pp. 57-61
Citations number
7
Categorie Soggetti
Oncology,"Biothechnology & Applied Migrobiology
Journal title
Journal of tumor marker oncology → ACNP
ISSN journal
08863849
Volume
11
Issue
1
Year of publication
1996
Pages
57 - 61
Database
ISI
SICI code
0886-3849(1996)11:1<57:PAPCOP>2.0.ZU;2-B
Abstract
UK101 extracted from normal goat liver consists of a glycoprotein of 5 0kDa and two proteins of 10 and 14kDa (UK110 and UK114), respectively. The biochemical methods described in our report allowed us to obtain UK110 and UK114 at an high degree of purity. UK110 was localized in cy toplasm and nucleus and its biochemical characteristics revealed a rem arkable similarity with ubiquitin. UK114 was localized at the level of cyplasm and it did not seem to be a protein known so far.