CERVICAL INTRAEPITHELIAL NEOPLASIA AND CERVICAL-CANCER

Cervical cancer remains an important health problem worldwide, despite its decline in countries where organized screening programs are in pl ace. The morbidity of treatment and mortality for advanced lesions are high, a frustrating situation because the cervix is accessible and a good screening test, the Pap smear, exists. Human papillomavirus infec tion is an important risk factor, and a vaccine against this virus cou ld be effective in eradicating this cancer. The cervix is a nearly per fect organ for chemoprevention studies because of its accessibility; e arly trials have been promising.