DEBLOCKING OF DITHIOACETALS AND OXATHIOACETALS USING PERIODIC ACID UNDER MILD NONAQUEOUS CONDITIONS

Authors
SHI XX KHANAPURE SP ROKACH J
Citation
Xx. Shi et al., DEBLOCKING OF DITHIOACETALS AND OXATHIOACETALS USING PERIODIC ACID UNDER MILD NONAQUEOUS CONDITIONS, Tetrahedron letters, 37(25), 1996, pp. 4331-4334
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
25
Year of publication
1996
Pages
4331 - 4334
Database
ISI
SICI code
0040-4039(1996)37:25<4331:DODAOU>2.0.ZU;2-7
Abstract
A novel method for the deblocking of the dithioacetals and oxathioacet als is described. Periodic acid under nonaqueous conditions has been u sed for the deprotection of the dithio- and oxathio-derivatives to the corresponding carbonyl compounds. This simple high-yield transformati on is conveniently carried out in nonaqueous medium and works well wit h complex sensitive aldehydes arid in the presence of other protective groups. Copyright (C) 1996 Elsevier Science Ltd.