PHOTO-SENSITIZED OXYGENATION OF PHENETHYLGUANIDOXIME - A POSSIBLE CHEMICAL-MODEL FOR THE BIOLOGICAL OXIDATION OF N-OMEGA-HYDROXY-L-ARGININETO L-CITRULLINE

Authors
ISHIKAWA T IKENO M SAKAMAKI T SATO K HIGUCHI K
Citation
T. Ishikawa et al., PHOTO-SENSITIZED OXYGENATION OF PHENETHYLGUANIDOXIME - A POSSIBLE CHEMICAL-MODEL FOR THE BIOLOGICAL OXIDATION OF N-OMEGA-HYDROXY-L-ARGININETO L-CITRULLINE, Tetrahedron letters, 37(25), 1996, pp. 4393-4396
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
25
Year of publication
1996
Pages
4393 - 4396
Database
ISI
SICI code
0040-4039(1996)37:25<4393:POOP-A>2.0.ZU;2-4
Abstract
Photo-sensitized oxygenation of phenethylguanidoxime led to the effect ive production of an expected urea derivative along with generation of nitric oxide (NO) or its equivalent. The formation of both products c ould be reasonably explained by the mechanism based on singlet oxygen ene reaction of olefins. This should give a possible chemical model fo r the biological oxidation of N-omega-hydroxy-L-arginine into L-citrul line and NO. Copyright (C) 1996 Elsevier Science Ltd