A computer simulation methodology is described that examines on a case
-specific basis the effect of water quality on the formation of trihal
omethanes (THMs) and their associated theoretical cancer risks. The st
rategy of controlling organic carbon concentrations at the point of ch
lorination was evaluated for its ability to reduce predicted cancer in
cidence. In waters containing bromide, the absolute concentrations of
the more brominated THMs can increase as organic carbon concentration
is reduced at the point of chlorination; total theoretical cancer risk
s induced by THMs, however, decreased for all water qualities consider
ed. Reduction of THM-induced cancer risks by enhanced coagulation, gra
nular activated carbon adsorption, and membrane filtration increased a
s the source water bromide concentration increased. When risks induced
by haloacetic acids are considered, these technologies may achieve si
gnificantly greater levels of risk reduction than are estimated by con
sidering THM risks only.