OBSERVATIONS ON THE TRANSMISSION OF SCRAPIE IN EXPERIMENTS USING EMBRYO-TRANSFER

Citation
Jd. Foster et al., OBSERVATIONS ON THE TRANSMISSION OF SCRAPIE IN EXPERIMENTS USING EMBRYO-TRANSFER, Veterinary record, 138(23), 1996, pp. 559-562
Citations number
15
Categorie Soggetti
Veterinary Sciences
Journal title
ISSN journal
00424900
Volume
138
Issue
23
Year of publication
1996
Pages
559 - 562
Database
ISI
SICI code
0042-4900(1996)138:23<559:OOTTOS>2.0.ZU;2-X
Abstract
This investigation studied the maternal transmission of scrapie in she ep by using embryo transfer to examine the viability of highly suscept ible offspring derived from scrapie-affected and uninfected donors. Th e study also examined the effect of washing the embryos, Scrapie occur red in both washed and unwashed embryo-derived Sip sAsA progeny from b oth groups of donor ewes, As a result, the earlier observation that sc rapie might pass via the unwashed embryo to develop as disease in adul t sheep has to be reassessed. Several other implications of the work a re considered, including the possibility that natural scrapie is not p urely a genetic disease.