The aim of this work is to extend the computerized method for process
pre-design to encompass safety aspects. Emphasis is on the choice betw
een different process concepts. The synthesis method is integrated int
o an existing computer aided process design tool. The method is based
on six databanks which contain hazardous properties of chemical compou
nds and knowledge of safe and unsafe process concepts. The first stage
of the method is a rule-based synthesis where safety rules are combin
ed with process rules. The second step includes a safety analysis of s
ynthetized alternatives which is done by calculating safety indices ba
sed on the safety properties of chemicals processed and the structure
and conditions of the process.