Background: The purpose of this study was to evaluate the usefulness o
f intraoperative ultrasonography (IOUS), a new method of imaging the b
iliary tree and related structures, during laparoscopic cholecystectom
y. Method: An IOUS probe (Aloka, Tokyo, Japan) with a 7.5-MHz linear-a
rray transducer was used during cholecystectomy in 124 patients with s
ymptomatic cholelithiasis (45 men, 79 women; mean age, 48 +/- 14 years
). Results: The examination of the common bile duct (CBD) was excellen
t in 117 patients but unsatisfactory in 7 cases (5.6%) at the level of
the head of the pancreas. In 5 patients, IOUS showed unsuspected chol
edocholithiasis: a subsequent intraoperational cholangiogram confirmed
this. In five cases IOUS was able to help the surgeon to localize a C
alot area obscured by inflammation. Postoperatively, one patient had a
n injury of the cystic duct stump: a nasobiliary tube resolved the bil
e leakage after 7 days. Another patient was submitted to postoperative
endoscopic retrograde cholangiopancreatography (ERCP) for a choledoch
olithiasis recognized by a trans-cystic-tube cholangiography: the ston
e was suspected but not demonstrated either by laparoscopic IOUS or by
intraoperative cholangiography. During the follow-up period, one pati
ent had an episode of acute pancreatitis. ERCP showed a small stone we
dged in the sphincter of Oddi. Conclusions: IOUS may be a real alterna
tive to cholangiography during laparoscopic cholecystectomy since it i
s safer and offers a complete examination of the biliary tree. It has
some disadvantages which can solved by additional experience.