PRECORE MUTANT OF HEPATITIS-B VIRUS PREVAILS IN ACUTE AND CHRONIC INFECTIONS IN AN AREA IN WHICH HEPATITIS-B IS ENDEMIC

Authors
CHU CM YEH CT CHIU CT SHEEN IS LIAW YF
Citation
Cm. Chu et al., PRECORE MUTANT OF HEPATITIS-B VIRUS PREVAILS IN ACUTE AND CHRONIC INFECTIONS IN AN AREA IN WHICH HEPATITIS-B IS ENDEMIC, Journal of clinical microbiology, 34(7), 1996, pp. 1815-1818
Citations number
26
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
34
Issue
7
Year of publication
1996
Pages
1815 - 1818
Database
ISI
SICI code
0095-1137(1996)34:7<1815:PMOHVP>2.0.ZU;2-1
Abstract
By using an amplification-create restriction site method, the precore TAG mutant of hepatitis B virus was detected in 6 (75%) of 8 acute ful minant hepatitis B patients, 7 (58%) of 12 acute self-limiting hepatit is B patients, 35 (81%) of 43 hepatitis B virus surface antigen carrie rs with fulminant hepatitis, and 42 (70%) of 60 hepatitis B virus surf ace antigen carriers with chronic hepatitis, The precore TAG mutant pr evails in acute and chronic hepatitis B of various severity in this ar ea where hepatitis B is endemic.