K. Boggian et al., INFREQUENT DETECTION OF LIPOARABINOMANNAN ANTIBODIES IN HUMAN IMMUNODEFICIENCY VIRUS-ASSOCIATED MYCOBACTERIAL DISEASE, Journal of clinical microbiology, 34(7), 1996, pp. 1854-1855
A commercially available test for the serologic diagnosis of tuberculo
sis was evaluated for its applicability in human immunodeficiency viru
s (HIV)-positive patients. Antibodies to lipoarabinomannan were detect
able in sera from only 9 of 85 HIV-positive patients with a confirmed
diagnosis of tuberculosis. Given the low degree of sensitivity of the
assay with sera from HIV-infected patients, the study does not support
the use of this serologic assay for the diagnosis of tuberculosis in
HIV-infected patients.