PRIMARY SCLEROSING CHOLANGITIS AND LIVER-TRANSPLANTATION

Primary sclerosing cholangitis is a chronic disease, strongly associat ed with ulcerative colitis and cholangiocarcinoma. Ulcerative colitis itself does not influence the liver transplant results. However; inten sified screening after liver transplantation for carcinoma of the colo n may be necessary. Cholangiocarcinoma, although incidentally found in hepatectomy specimens, has a bad prognosis; Initial reports in the li terature indicate a far lower survival when liver transplantation is p erformed for PSC, in comparison to the results achieved in other trans plant indications. This might have been due to surgical interventions which nowadays are avoided. Later reports show a better prognosis than the initial ones. We report on the results of liver transplantation f or PSC, as indicated in the literature and on the results of the Groni ngen transplant centre.