SIMULTANEOUS PRESENTATION OF SYMPTOMATIC SUBEPENDYMOMAS IN SIBLINGS -CASE-REPORTS AND REVIEW

Authors
CHENG TM COFFEY RJ GELBER BR SCHEITHAUER BW
Citation
Tm. Cheng et al., SIMULTANEOUS PRESENTATION OF SYMPTOMATIC SUBEPENDYMOMAS IN SIBLINGS -CASE-REPORTS AND REVIEW, Neurosurgery, 33(1), 1993, pp. 145-150
Citations number
117
Categorie Soggetti
Surgery,Neurosciences
Journal title
Neurosurgery → ACNP
ISSN journal
0148396X
Volume
33
Issue
1
Year of publication
1993
Pages
145 - 150
Database
ISI
SICI code
0148-396X(1993)33:1<145:SPOSSI>2.0.ZU;2-2
Abstract
TWO YOUNG ADULT siblings independently developed similar neurological complaints that included headaches, photophobia, nausea, and intermitt ent lancinating facial pains. Magnetic resonance imaging revealed four th ventricular lesions that required surgery in both patients. A patho logical review revealed subependymomas with virtually identical histol ogical features. The clinical features and common pathological finding s of both patients suggest that familial subependymomas may have a mal developmental origin with genetic implications.