ACHIEVING NATURAL PRODUCT SYNTHESIS AND DIVERSITY VIA CATALYTIC NETWORKING EX-VIVO

Authors
ROESSNER CA SCOTT AI
Citation
Ca. Roessner et Ai. Scott, ACHIEVING NATURAL PRODUCT SYNTHESIS AND DIVERSITY VIA CATALYTIC NETWORKING EX-VIVO, Chemistry & biology, 3(5), 1996, pp. 325-330
Citations number
31
Categorie Soggetti
Biology
Journal title
Chemistry & biology → ACNP
ISSN journal
10745521
Volume
3
Issue
5
Year of publication
1996
Pages
325 - 330
Database
ISI
SICI code
1074-5521(1996)3:5<325:ANPSAD>2.0.ZU;2-6
Abstract
Recent studies on ex vivo synthesis of natural products reveal that ev en complex multistep pathways can be successfully reconstructed. Genet ic engineering of such reconstituted pathways has already been used to generate 'unnatural' natural products related to the original compoun d. In the future, it may be possible to use these approaches to make n atural products that are currently inaccessible to conventional synthe sis.