B. Lettgen et al., ANTENATAL SONOGRAPHY OF THE KIDNEYS AND U RINARY-TRACT - POSSIBILITIES, USES, DANGERS, Monatsschrift fur Kinderheilkunde, 141(6), 1993, pp. 462-467
Congenital abnormalities of the urinary tract can be detected as early
as during the 15th-18th week of gestation. Nevertheless, most abnorma
lities are detected between the 28th-30th week of gestation. Antenatal
fetal abnormalities vary between physiological dilatation to bilatera
l hydronephrosis and polycystic kidney desease. Abnormalities in anten
atal fetal ultrasonography are found in 0.5% of all pregnancies, 30-50
% of these abnormalities are related to the urinary tract. Though most
of the abnormalities are diagnosed late in pregnancy, irreversible da
mage of the kidneys has already taken place by that time and the fetus
will not profit from antenatal therapy. On the other hand, a fetus wi
th late onset of urinary tract obstruction may profit from antenatal i
ntervention or early labor. Repeated ultrasonography is crucial for in
itiating further invasive diagnostic procedures, antenatal therapy and
for planing the time of labor. There is a great risk of overdiagnosin
g and inadequate therapy because too little is known about physiologic
al development of the fetal urinary tract in ultrasonography and so ph
ysiological and pathological development cannot be differentiated safe
ly.