CYTOTOXIC OXYGENATED DESMOSTEROLS OF THE RED ALGA GALAXAURA-MARGINATA

Authors
SHEU JH HUANG SY DUH CY
Citation
Jh. Sheu et al., CYTOTOXIC OXYGENATED DESMOSTEROLS OF THE RED ALGA GALAXAURA-MARGINATA, Journal of natural products, 59(1), 1996, pp. 23-26
Citations number
20
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
59
Issue
1
Year of publication
1996
Pages
23 - 26
Database
ISI
SICI code
0163-3864(1996)59:1<23:CODOTR>2.0.ZU;2-Z
Abstract
Desmosterol (1), 24,25-epoxycholesterol (2), 24-hydroperoxycholesta-5, 25-dien-3 beta-ol (3), 25-hydroperoxycholesta-5,23(E)-dien-3 beta-ol ( 4), cholesta-5,25-diene-3 beta,24-diol (5), and 24,25-epoxy-6 beta-hyd roxycholest-4-en-3-one (7) were isolated from the marine red alga Gala xaura marginata; sterols 3, 4, and 7 were isolated for the first time from a natural source. Sterols 3-7 exhibited significant cytotoxicity toward serveral cancer cell lines.