ANTICOAGULANT ACTIVITY OF TRIATOMA-INFESTANS AND PANSTRONGYLUS-MEGISTUS-SALIVA (HEMIPTERA TRIATOMINAE)/

Citation
Mh. Pereira et al., ANTICOAGULANT ACTIVITY OF TRIATOMA-INFESTANS AND PANSTRONGYLUS-MEGISTUS-SALIVA (HEMIPTERA TRIATOMINAE)/, Acta Tropica, 61(3), 1996, pp. 255-261
Citations number
21
Categorie Soggetti
Tropical Medicine",Parasitiology
Journal title
ISSN journal
0001706X
Volume
61
Issue
3
Year of publication
1996
Pages
255 - 261
Database
ISI
SICI code
0001-706X(1996)61:3<255:AAOTAP>2.0.ZU;2-P
Abstract
Salivary gland extract of Triatoma infestans prolonged thrombin time, prothrombin time, and activated partial thromboplastin time, while sal ivary gland extract of Panstrongylus mesgistus delayed thrombin time a nd activated partial thromboplastin time. However, saliva of P. megist us prolonged activated partial thromboplastin time and saliva of T. in festans delayed activated partial thromboplastin time and prothrombin time. T. infestans saliva interferes particularly with activity of fac tor VIII (intrinsic pathway) and factor V (common pathway), but also a ffects other factors. Saliva of the triatomine species studied present ed distinct SDS-PAGE profiles. These results demonstrate that there ar e differences in anticoagulant activity and protein composition of tri atomine saliva.