POLYMORPHISM OF AZLOCILLIN SODIUM

Citation
Gn. Kalinkova et S. Stoeva, POLYMORPHISM OF AZLOCILLIN SODIUM, International journal of pharmaceutics, 135(1-2), 1996, pp. 111-114
Citations number
14
Categorie Soggetti
Pharmacology & Pharmacy
ISSN journal
03785173
Volume
135
Issue
1-2
Year of publication
1996
Pages
111 - 114
Database
ISI
SICI code
0378-5173(1996)135:1-2<111:POAS>2.0.ZU;2-E
Abstract
The polymorphism of azlocillin sodium (AZ) has not been discussed suff iciently in the literature. The results of infrared (TR)spectroscopy, thermal analysis (combined thermogravimetry TG and differential analys is DTA), and scanning electron microscopy (SEM) confirm that recrystal lization of lyophilized azlocillin sodium from simple solvent acetonit rile causes polymorphic transformation. The new polymorph obtained by us has a crystalline form.