THE SHIKIMATE PATHWAY .8. SYNTHESIS OF INO-4(R),5(R)-DIHYDROXY-1-CYCLOHEXENE-1-CARBOXYLIC ACID - THE 3(R)-AMINO ANALOG OF (-)-SHIKIMIC ACID

Authors
ADAMS H BAILEY NA BRETTLE R CROSS R FREDERICKSON M HASLAM E MACBEATH FS DAVIES GM
Citation
H. Adams et al., THE SHIKIMATE PATHWAY .8. SYNTHESIS OF INO-4(R),5(R)-DIHYDROXY-1-CYCLOHEXENE-1-CARBOXYLIC ACID - THE 3(R)-AMINO ANALOG OF (-)-SHIKIMIC ACID, Tetrahedron, 52(25), 1996, pp. 8565-8580
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
25
Year of publication
1996
Pages
8565 - 8580
Database
ISI
SICI code
0040-4020(1996)52:25<8565:TSP.SO>2.0.ZU;2-Z
Abstract
The first successful method for the introduction of nitrogenous functi onality at C-3 of the shikimate nucleus has been developed and has all owed the synthesis of ino-4(R),5(R)-dihydroxy-1-cyclohexene-1-carboxyl ic acid [the 3(R)-amino analogue of (-)-shikimic acid] in seven steps from the parent acid. (C) 1996 Elsevier Science Ltd