Eighteen patients with advanced giant cell tumors were treated with co
mplete tumor resection and reconstruction using fresh osteochondral al
lografts. All patients had one or more of the following indications fo
r tumor resection (as opposed to curettage): tumor recurrence, patholo
gical fracture, or destruction of the subchondral bone plate. At the 4
- to 16-year follow-up (mean 9 years), two grafts were revised to a se
cond fresh graft because of fracture, one graft was converted to an al
lograft implant compositie and two joints were fused because of infect
ion. The functional results were assessed in 14 patients: 9 were good
or excellent, 4 fair and 1 poor. We conclude that the fresh osteochond
ral allograft is a viable treatment alternative to prosthetic replacem
ent in advanced benign, aggressive bone tumors.