D-AMPHETAMINE CHALLENGE EFFECTS ON WISCONSIN CARD SORT TEST - PERFORMANCE IN SCHIZOTYPAL PERSONALITY-DISORDER

Authors
SIEGEL BV TRESTMAN RL OFLAITHBHEARTAIGH S MITROPOULOU V AMIN F KIRRANE R SILVERMAN J SCHMEIDLER J KEEFE RSE SIEVER LJ
Citation
Bv. Siegel et al., D-AMPHETAMINE CHALLENGE EFFECTS ON WISCONSIN CARD SORT TEST - PERFORMANCE IN SCHIZOTYPAL PERSONALITY-DISORDER, Schizophrenia research, 20(1-2), 1996, pp. 29-32
Citations number
12
Categorie Soggetti
Psychiatry,Psychiatry,"Clinical Neurology
Journal title
Schizophrenia research → ACNP
ISSN journal
09209964
Volume
20
Issue
1-2
Year of publication
1996
Pages
29 - 32
Database
ISI
SICI code
0920-9964(1996)20:1-2<29:DCEOWC>2.0.ZU;2-H
Abstract
The authors assessed the effects on Wisconsin Card Sort (WCST) perform ance and psychiatric symptoms of 30 mg d-amphetamine, a dopamine and n orepinephrine agonist, vs placebo in nine patients with schizotypal pe rsonality disorder (SPD). Patients, particularly those who made more p erseverative errors, demonstrated amphetamine-associated improvement o n WCST performance. The data in this preliminary study suggest that so me of the cognitive dysfunction present in SPD may improve with amphet amine challenge.