Ja. Matochik et al., NEUROPSYCHOLOGICAL CORRELATES OF FAMILIAL ATTENTION-DEFICIT HYPERACTIVITY DISORDER IN ADULTS, Neuropsychiatry, neuropsychology, and behavioral neurology, 9(3), 1996, pp. 186-191
To determine the neuropsychological correlates of attention-deficit hy
peractivity disorder (ADHD) in adults, we examined 21 subjects (16 mal
es, 5 females) with childhood-onset and familial ADHD (i.e., biologica
l parents of children with ADHD) with the Wechsler Adult Intelligence
Scale-Revised (WAIS-R), the Wide Range Achievement Test-Revised (WRAT-
R), Gray Oral Reading Test, and the Wisconsin Card Sorting Test. Consi
stent with findings in children with ADHD, Freedom from Distractibilit
y (Arithmetic and Digit Span subtests) was decreased relative to the V
erbal Comprehension and Perceptual Organization factors on the WAIS-R
for the group as a whole, with seven subjects (33%) demonstrating sign
ificant attentional deficits when either factor or individual subtest
profiles were considered. Although six men (29% of sample) met regress
ion-based criteria for reading/spelling disabilities, only two of thes
e subjects showed absolute deficits in reading and spelling. None show
ed a comorbid arithmetic disorder. Wisconsin Card Sort performance fel
l within normal limits for all but three subjects. The lack of signifi
cant deficits on our test battery suggest that future studies should a
ddress test sensitivity issues and include a broader assessment of the
impact of ADHD symptoms on daily social functioning in adults.