Mt. Gutierrezlugo et al., ANTIMICROBIAL AND CYTOTOXIC ACTIVITIES OF SOME CRUDE DRUG EXTRACTS FROM MEXICAN MEDICINAL-PLANTS, Phytomedicine, 2(4), 1996, pp. 341-347
31 crude extracts derived from 28 plants highly valued as anti-infecti
ve agents in Mexican folk medicine have been screened for antimicrobia
l activity against four bacteria, a yeast and two molds. The results o
f the quantitative study indicated that the extracts derived from five
species (Malmea depressa, Heliopsis longipes, Datura lanosa, Cnidoscu
lus tehuacanensis and Helianthella quinquenervis) possessed significan
t antiseptic properties, therefore supporting the ethnomedical uses of
these species. The cytotoxic activity was assayed against three cell
lines HT-29 (Colon adenocarcinoma), MCF-7 (Breast carcinoma), A-549 (L
ung carcinoma) and only the extract of Helianthella quinquenervis poss
essed significant activity against the MCF-7 cell line.