CONSERVATION TREATMENT IN SUBAREOLAR BREAST CANCERS

The results of centromammary conservation in 37 patients with 20 mm-me dian-size breast cancer, located in the subareolar area (SAA), with an infiltration of the nipple-areolar-complex (NAC) in 12 patients and a retraction in 24, are reported, Breast conservative surgery was initi ally performed in 30 patients; five patients were first treated with c hemotherapy; two patients received initial tamoxifen, Surgery comprise d tumorectomy plus axillary dissection, with complete resection of the NAC (20 patients), or partial resection (nine patients), or without r esection (eight patients). Post-operatively, all patients received 50 Gy external radiotherapy, with an additional external electron boost i n 13 patients; 14 patients received adjuvant tamoxifen and two patient s adjuvant chemotherapy. With a median follow-up of 49 months, one pat ient experienced a local failure and four a metastatic failure; 5-year overall actuarial survival and disease-free survival rates were 97% a nd 75%, Cosmetic results were excellent in three patients, good in 25, and poor in seven. Breast conservation appears a satisfying treatment in small breast cancer located in SAA.