Bone hardness of 10 human patellas in 15 regions and at three depths w
as measured through in situ indentation tests. Indentation tests were
performed perpendicular to the three articular surfaces (lateral and m
edial facets, and central ridge area) and, thus, parallel to the trabe
culae. Multiple regression analysis demonstrated a significant reducti
on of bone hardness with depth. In addition, the lateral facet had a h
igher bone hardness than the medial facet, and the proximal and centra
l regions demonstrated higher bone hardness than the distal region. Ov
erall, the proximolateral region of the patella exhibited the highest
hardness compared with other regions. As bone hardness is indicative o
f load bearing, these results may have important consequences for pate
llar resurfacing and patellar component design.