SELECTIVE ANTIMICROBIAL ACTIVITIES OF MITRACARPUS SCABER ZUCC AGAINSTCANDIDA AND STAPHYLOCOCCUS SP

Different extracts of Mitracarpus scaber aerial parts were investigate d for in vitro antibacterical and antimycotic activities against strai ns of laboratory microorganisms and clinical isolates responsible for skin infections. The diethyl ether extract possesses a rather good act ivity: the minimum inhibitory concentration ranged from 15.6-31.25 mu g/ml against standard strains of Candida sp. and from 7.8-125 mu g/ml against clinical isolates strains. Staphylococci were inhibited at 3.9 -62.5 mu g/ml (standard strains) and at 1.9-15.6 mu g/ml (clinical iso lates). The results confirm the rationale of the folkloric use of Mitr acarpus in treating fungal and bacterial infections.