En. Mccomb et al., CHROMOSOMAL-ANOMALIES EXCLUSIVE OF TELOMERIC ASSOCIATIONS IN GIANT-CELL TUMOR OF BONE, Cancer genetics and cytogenetics, 88(2), 1996, pp. 163-166
The occurrence of telomeric associations in giant cell tumor of bone i
s well recognized. However, there has been little emphasis on clonal s
tructural abnormalities that may be seen in addition to or in the abse
nce of telomeric associations. Two cases of giant cell tumor of bone a
re presented in this study demonstrating clonal karyotypic anomalies o
ther than telomeric association with a review of previously reported c
ases showing similar findings.