DELIVERY OF PEPTIDES INTO THE CENTRAL-NERVOUS-SYSTEM

Research into the delivery of potentially useful peptide therapeutic a gents to the CNS has lagged behind the exponential growth in their dis covery. There remain many problems in developing effective and safe de livery strategies, but there has been some progress in overcoming this major obstacle, The author provides an overview of those properties o f the blood-brain barrier that are specific for pep tides and outlines current methods addressing peptide drug delivery to the CNS.