MAURITIAMINE, A NEW ANTIFOULING OROIDIN DIMER FROM THE MARINE SPONGE AGELAS-MAURITIANA

Authors
TSUKAMOTO S KATO H HIROTA H FUSETANI N
Citation
S. Tsukamoto et al., MAURITIAMINE, A NEW ANTIFOULING OROIDIN DIMER FROM THE MARINE SPONGE AGELAS-MAURITIANA, Journal of natural products, 59(5), 1996, pp. 501-503
Citations number
15
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
59
Issue
5
Year of publication
1996
Pages
501 - 503
Database
ISI
SICI code
0163-3864(1996)59:5<501:MANAOD>2.0.ZU;2-9
Abstract
A new oroidin dimer, mauritiamine (1), has been isolated from the mari ne sponge Agelas mauritiana along with the known oroidin (2) and 4,5-d ibromopyrrole-2-carbamide (3). Their structures were determined by spe ctral analysis. Compounds 1 and 2 inhibited larval metamorphosis of th e barnacle Balanus amphitrite with ED(50) values of 15 and 19 mu g/mL, respectively, while 3 promoted larval metamorphosis of the ascidian C iona savignyi at a concentration of 2.5 mu g/mL.