GLOBOSTELLATIC ACIDS A-D, NEW CYTOTOXIC ISOMALABARICANE TRITERPENES FROM THE MARINE SPONGE STELLETTA-GLOBOSTELLATA

Authors
RYU G MATSUNAGA S FUSETANI N
Citation
G. Ryu et al., GLOBOSTELLATIC ACIDS A-D, NEW CYTOTOXIC ISOMALABARICANE TRITERPENES FROM THE MARINE SPONGE STELLETTA-GLOBOSTELLATA, Journal of natural products, 59(5), 1996, pp. 512-514
Citations number
10
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
59
Issue
5
Year of publication
1996
Pages
512 - 514
Database
ISI
SICI code
0163-3864(1996)59:5<512:GAANCI>2.0.ZU;2-J
Abstract
Four new cytotoxic triterpenes, globostellatic acids A-D (1-4), have b een isolated from the marine sponge Stelletta globostellata. Their str uctures have been determined by interpretation of spectral data. They exhibited cytotoxicity against P-388 murine leukemia cells with IC50 v alues of 0.1-0.46 mu g/mL.