SYNTHESIS OF -4-FORMYLPYRAZOL-1-YL)-3-PHENYL-1,8-NAPHTHYRIDINES

Citation
Js. Rao et al., SYNTHESIS OF -4-FORMYLPYRAZOL-1-YL)-3-PHENYL-1,8-NAPHTHYRIDINES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 35(7), 1996, pp. 713-714
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
03764699
Volume
35
Issue
7
Year of publication
1996
Pages
713 - 714
Database
ISI
SICI code
0376-4699(1996)35:7<713:SO->2.0.ZU;2-C
Abstract
-4-formylpyrazol-1-yl)-3-phenyl-1,8-naphthyridines (3) have been synth esized by the reaction of acetophenone 3-phenyl-1,8-naphthyridin-2-ylh ydrazones (2) with POCl3 and DME The intermediate hydrazones 2 in turn are prepared by the condensation of 2-hydrazino-3-phenyl-1,8-naphthyr idine (1) with different acetophenones. 1,8-Naphthyridines 3 have been characterized on the basis of their elemental analyses and spectral ( IR,H-1 NMR and mass) data and tested for their antibacterial activity.