Js. Rao et al., SYNTHESIS OF -4-FORMYLPYRAZOL-1-YL)-3-PHENYL-1,8-NAPHTHYRIDINES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 35(7), 1996, pp. 713-714
-4-formylpyrazol-1-yl)-3-phenyl-1,8-naphthyridines (3) have been synth
esized by the reaction of acetophenone 3-phenyl-1,8-naphthyridin-2-ylh
ydrazones (2) with POCl3 and DME The intermediate hydrazones 2 in turn
are prepared by the condensation of 2-hydrazino-3-phenyl-1,8-naphthyr
idine (1) with different acetophenones. 1,8-Naphthyridines 3 have been
characterized on the basis of their elemental analyses and spectral (
IR,H-1 NMR and mass) data and tested for their antibacterial activity.