R. Gupta et al., REACTION OF 3-SUBSTITUTED-4-AMINO-5-MERCAPTO-1,2,4-TRIAZOLES WITH SUBSTITUTED CINNAMIC-ACIDS, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 35(7), 1996, pp. 718-720
Various 2,4-dialkoxy-5-ethylcinnamic acids (2) when condensed with 3-s
ubstituted-4-amino-5-mercapto-1,2,4-triazoles (3) in the presence of p
hosphorus oxychloride give lkoxy-5'-alkylphenyl)ethen-1-yl]-s-triazolo
[3,4-b] [1,3,4]thiadiazoles (4) whose structures have been established
on the basis of analytical and spectral data. The thiadiazoles 4 have
been assessed for antiinflammatory, antibacterial and antifungal acti
vities.