REACTION OF 3-SUBSTITUTED-4-AMINO-5-MERCAPTO-1,2,4-TRIAZOLES WITH SUBSTITUTED CINNAMIC-ACIDS

Citation
R. Gupta et al., REACTION OF 3-SUBSTITUTED-4-AMINO-5-MERCAPTO-1,2,4-TRIAZOLES WITH SUBSTITUTED CINNAMIC-ACIDS, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 35(7), 1996, pp. 718-720
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
03764699
Volume
35
Issue
7
Year of publication
1996
Pages
718 - 720
Database
ISI
SICI code
0376-4699(1996)35:7<718:RO3WS>2.0.ZU;2-K
Abstract
Various 2,4-dialkoxy-5-ethylcinnamic acids (2) when condensed with 3-s ubstituted-4-amino-5-mercapto-1,2,4-triazoles (3) in the presence of p hosphorus oxychloride give lkoxy-5'-alkylphenyl)ethen-1-yl]-s-triazolo [3,4-b] [1,3,4]thiadiazoles (4) whose structures have been established on the basis of analytical and spectral data. The thiadiazoles 4 have been assessed for antiinflammatory, antibacterial and antifungal acti vities.